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Anti-TNF-α (Golimumab), Human IgG1 Antibody

Supplier:
Catalogue number:
A2141-100
Size:
100 µg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£581.00 Estimated delivery Wed 30 Jun
Shipping is calculated in checkout

Golimumab is a human IgG1 kappa monoclonal antibody derived from HuMab transgenic mice immunised with human tumor necrosis factor alpha (TNF-α). This antibody targets and neutralises soluble as well as transmembrane human TNF-α, which plays a key role in chronic inflammatory diseases such as Rheumatoid arthritis, inflammatory bowel disease, Crohn’s disease, Psoriatic arthritis, and ankylosing spondylitis. Golimumab was developed by Janssen Biotech and received FDA approval in 2009 for the treatment of Rheumatoid Arthritis, Psoriatic Arthritis, and ankylosing spondylitis (AS). Additionally, in 2013, this antibody received approval for the treatment of ulcerative colitis. Golimumab is marketed under the trade name SIMPONI®

Product Type:

Antibodies

Species Reactivity:

Human

Storage Temp:

-80°C

Antibody Host:

Recombinant

Antibody Isotype:

IgG1, kappa

Formulation:

In PBS, pH 7.5

Antibody Type:

Monoclonal

UNSPSC Code:

12352203

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