Anti-VEGFR2 (Ramucirumab), Human IgG1 Antibody
Catalogue number:
A2139-100
Supplier:
BioVision
Size:
100 µg _$$_
Product is available in:
N/A
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This product is no longer available to order.
Applications:
In vitro studies
Antibody Host:
Human
Species Reactivity:
Human
Antibody Isotype:
IgG1, kappa
Antibody Type:
Monoclonal
Immunogen:
Ramucirumab
- Data sheet: View or download
Product Description:
The research-grade biosimilar is a fully human IgG1 monoclonal antibody that binds to the vascular endothelial growth factor receptor 2 (VEGFR2) and inhibits association with its ligands (VEGF A, C, and D). This prevents VEGF-mediated proliferation, migration of endothelial cells, and angiogenesis. The original monoclonal antibody received FDA approval to treat advanced gastric cancer/gastro-esophageal junction (GEJ) adenocarcinoma. It is also approved for use for the combination treatment of metastatic non-small lung carcinoma (NSLC), metastatic colorectal cancer (mCRC), and hepatocellular carcinoma (HCC).
Storage Temperature:
-80°C