Anti-C5, Humanized Antibody
Catalogue number:
A2138-100
Supplier:
BioVision
Size:
100 µg _$$_
Product is available in:
N/A
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This product is no longer available to order.
Antibody Host:
Recombinant
Species Reactivity:
Human
Antibody Isotype:
IgG2/4, kappa
Antibody Type:
Monoclonal
Immunogen:
Eculizumab
- Data sheet: View or download
Product Description:
The research-grade biosimilar is a recombinant humanized IgG2/4 kappa monoclonal antibody that inhibits the cleavage of C5 into C5a and C5b by C5 convertases. Inhibition of C5 cleavage prevents the generation of the terminal complement complex C5b-9. Both C5a and C5b-9 have proinflammatory and prothrombic properties and play a significant role in complement-mediated diseases such as paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS).
Storage Temperature:
-80°C