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Anti-C5, Humanized Antibody

Catalogue number:
Supplier:
BioVision
Size:
100 µg _$$_
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
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Antibody Host:

Recombinant

Species Reactivity:

Human

Antibody Isotype:

IgG2/4, kappa

Antibody Type:

Monoclonal

Immunogen:

Eculizumab

Product Description:

The research-grade biosimilar is a recombinant humanized IgG2/4 kappa monoclonal antibody that inhibits the cleavage of C5 into C5a and C5b by C5 convertases. Inhibition of C5 cleavage prevents the generation of the terminal complement complex C5b-9. Both C5a and C5b-9 have proinflammatory and prothrombic properties and play a significant role in complement-mediated diseases such as paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS).

Storage Temperature:

-80°C