Anti-IL-6Rα (Sarilumab), Human IgG1 Antibody
Catalogue number:
A2133-100
Supplier:
BioVision
Size:
100 µg _$$_
Product is available in:
N/A
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Applications:
In vitro and In vivo studies
Antibody Host:
Recombinant
Antibody Isotype:
Human IgG1
Antibody Type:
Monoclonal
Immunogen:
Sarilumab
- Data sheet: View or download
Product Description:
The research-grade biosimilar is a fully human anti-IL-6R monoclonal IgG1 antibody that can bind to membrane as well as soluble forms of interleukin 6 receptor (IL-6R). This leads to inhibition of IL-6 mediated signaling and reduced release of CRP, serum amyloid A and fibrinogen, which are potential biomarkers of rheumatoid arthritis (RA). The original monoclonal antibody received US-FDA approval in 2017 to treat moderate to severe RA in combination with methotrexate. The original antibody is currently being evaluated for phase 3 clinical trial on COVID-19 patients
Storage Temperature:
4°C