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ITE

Supplier:
Catalogue number:
CAY25355-25 mg
Size:
25 mg
Product is available in:
  • UK
  • Ireland
  • Europe
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£164.00 Estimated delivery Fri 18 Jun
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An endogenous AhR agonist; binds to AhR (Kd = 65 nM) and induces AhR-dependent transcription in luciferase reporter assays at 0.01 µM; inhibits anti-CD40- and IL-4-induced differentiation of isolated mouse splenic B cells, as well as proliferation and migration of SKOV3 ovarian cancer cells at 1 µM; reduces retinal detachment and ocular inflammatory cell infiltration in a mouse model of experimental autoimmune uveitis induced by CFA and M. tuberculosis at 200 µg/animal; reduces tumor growth by 39% in an OVCAR-3 mouse xenograft model at 80 mg/kg

Product Type:

Biochemicals

CAS Number:

448906-42-1

Alternative Names:

2-(1h-indol-3-ylcarbonyl)-4-thiazolecarboxylic acid, methyl ester

Storage Temp:

-20°C

Formulation:

A solid

Compound Purity:

≥98%

UNSPSC Code:

12352100

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