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Dofequidar

Supplier:
Catalogue number:
CAY30925-1 mg
Size:
1 mg
Product is available in:
  • UK
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£45.00 Estimated delivery Fri 18 Jun
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A quinoline derivative and inhibitor of multidrug resistance; inhibits P-glycoprotein in a photolabeling assay at 100 µM; increases intracellular accumulation of [3H]-vincristine in HL-60R cells endogenously expressing the gene encoding MRP at 10 µM; restores susceptibility to vincristine- or doxorubicin-induced cytotoxicity in vincristine-resistant P388, vincristine-resistant K562, and doxorubicin-resistant K562 cells; increases survival in a vincristine-resistant P388 murine leukemia model compared with untreated controls at 80 mg/kg twice per day when administered in combination with vincristine

Product Type:

Biochemicals

CAS Number:

129716-58-1

Alternative Names:

1-[4-[2-hydroxy-3-(5-quinolinyloxy)propyl]-1-piperazinyl]-2,2-diphenyl-ethanone

Storage Temp:

-20°C

Formulation:

A solid

Compound Purity:

≥98%

UNSPSC Code:

12352100

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