Protriptyline (hydrochloride)
Catalogue number:
CAY31179-10 mg
Supplier:
Size:
10 mg _$$_
Product is available in:
£74.00
Estimated delivery Wed 1 May
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1225-55-4
Purity:
≥98%
Formulation:
A solid
Molecular Weight:
299.8
Alternative Names:
n-methyl-5h-dibenzo[a,d]cycloheptene-5-propanamine, monohydrochloride, protryptyline
- Data sheet: View or download
- MSDS: View or download
Product Description:
A tricyclic antidepressant; binds to the norepinephrine and 5-HT transporters (Kd = 1.41 and 19.6 nM, respectively); binds to histamine H1, muscarinic acetylcholine, and α1-adrenergic receptors (Kds = 25, 25, and 130 nM, respectively); inhibits norepinephrine uptake into rat whole brain and hypothalamic synaptosomes (IC50s = 12 and 0.55 µM, respectively) and 5-HT uptake into rat whole brain synaptosomes (IC50 = 5.5 µM); inhibits food-induced cataplexy in narcoleptic dogs at 1 mg/kg, i.v.
Storage Temperature:
-20°C