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Fluorobexarotene

Supplier:
Catalogue number:
CAY30933-1 mg
Size:
1 mg
Product is available in:
  • UK
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£61.00 Estimated delivery Thu 1 Jul
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An RXRα agonist; binds to RXRα (Ki = 12 nM) and induces RXRα-mediated transcription in a mammalian two-hybrid assay (EC50 = 43 nM); an RAR agonist, inducing 25% of the activity of all-trans retinoic acid at 100 nM; enhances basolateral-to-apical transport of a fluorescent Aβ42 in an in vitro BBB model at 5 and 10 µM; increases brain-to-peripheral transport of Aβ42 by 3.3-fold in wild-type, but not ApoE knockout, mice at 20 mg/kg, i.p.

Product Type:

Biochemicals

CAS Number:

1190848-23-7

Alternative Names:

2-fluoro-4-[1-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]-benzoic acid

Storage Temp:

-20°C

Formulation:

A solid

Compound Purity:

≥95%

UNSPSC Code:

12352100

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