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Phillygenin

Supplier:
Catalogue number:
CAY30698-10 mg
Size:
10 mg
Product is available in:
  • UK
  • Ireland
  • Europe
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  • Rest of World
£49.00 Estimated delivery Tue 22 Jun
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A lignan with diverse biological activities; scavenges peroxide and DPPH radicals in cell-free assays (IC50s = 10.5 and 19.1 µM, respectively); inhibits LPS-induced production of IL-1β, IL-6, TNF-α, and the fibrosis markers collagen I and α-SMA in LX-2 hepatic stellate cells from 25-200 µg/ml; inhibits the growth of SH-1-V1 esophageal cancer cells (IC50 = 6 µM), as well as induces the production of ROS and apoptosis in the same cells; reduces tumor volume in an SH-1-V1 mouse xenograft model at 15 mg/kg; reduces serum levels of ALT, AST, SOD, and MDA and prevents hepatic necrosis in a mouse model of carbon tetrachloride-induced liver injury

Product Type:

Biochemicals

CAS Number:

487-39-8

Alternative Names:

4-[(1s,3ar,4r,6ar)-4-(3,4-dimethoxyphenyl)tetrahydro-1h,3h-furo[3,4-c]furan-1-yl]-2-methoxy-phenol, (+)-phillygenin, epipinoresinol methyl ether

Storage Temp:

-20°C

Formulation:

A crystalline solid

Compound Purity:

≥95%

UNSPSC Code:

12352200

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