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JNJ-17203212

Supplier:
Catalogue number:
CAY30930-25 mg
Size:
25 mg
Product is available in:
  • UK
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£325.00 Estimated delivery Fri 18 Jun
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A TRPV1 antagonist (Ki = 72 nM for the recombinant guinea pig channel); inhibits capsaicin- or pH decrease-induced guinea pig TRPV1 channel activation (IC50s = 58 and 470 nM, respectively); reduces the number of citric acid- or capsaicin-induced coughs in guinea pigs at 20 mg/kg; reduces spontaneous and palpitation-induced flinching and guarding in a mouse model of bone cancer pain at 30 mg/kg; decreases capsaicin-induced production of CGRP and inflammatory soup-induced trigeminal expression of cfos in rat models of migraine

Product Type:

Biochemicals

CAS Number:

821768-06-3

Alternative Names:

4-[3-(trifluoromethyl)-2-pyridinyl]-n-[5-(trifluoromethyl)-2-pyridinyl]-1-piperazinecarboxamide

Storage Temp:

-20°C

Formulation:

A crystalline solid

Compound Purity:

≥98%

UNSPSC Code:

12352202

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