Alloisolithocholic Acid
Catalogue number:
CAY29542-10 mg
Supplier:
Size:
10 mg _$$_
Product is available in:
£168.00
Estimated delivery Fri 3 May
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2276-93-9
Purity:
≥95%
Formulation:
A solid
Molecular Weight:
376.6
Alternative Names:
(5α)-3β-hydroxy-cholan-24-oic acid, ailca, alloisolca, isoallolca, isoallolithocholic acid, nsc 18169, β-hydroxy-5-cholenoic acid
- Data sheet: View or download
- MSDS: View or download
Product Description:
A metabolite of dehydrolithocholic acid; increases the association of Nr4a1 to the Foxp3 gene locus in isolated mouse CD4+ T cells at 20 µM; induces differentiation of isolated mouse T cells into Tregs and the production of mitochondrial ROS in isolated mouse CD4+ T cells at 20 µM; reduces hepatic bile flow and bile salt, cholesterol, and phospholipid secretion, as well as induces loss of microvilli and dilation of canaliculi in hepatocytes in rats at 6 mg/kg; fecal levels are reduced in patients with Crohn's disease or ulcerative colitis
Storage Temperature:
-20°C