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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
85416-75-7
Purity:
≥98%
Formulation:
A solid
Molecular Weight:
275.3
Alternative Names:
(4r)-4-[3-(cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone, (r)-(–)-rolipram, (r)-rolipram
- Data sheet: View or download
- MSDS: View or download
Product Description:
A PDE4 inhibitor (IC50 = 0.22 µM for the guinea pig eosinophil enzyme); enhances isoprenaline-induced cAMP accumulation in isolated guinea pig eosinophils (EC50 = 0.19 µM); inhibits TNF and INF-γ production in L1402 CD4+ encephalitogenic rat T cells from 1-1,000 µM; inhibits ovalbumin-induced contraction of tracheal rings isolated from ovalbumin-sensitized guinea pigs at 1 µM; inhibits ovalbumin-induced bronchoconstriction in guinea pigs (ED50 = 0.25 mg/kg)
Storage Temperature:
-20°C