www.bioscience.co.uk
Sales & Support: +44 (0)1223 316 855

*

PD 180970

Catalogue number:
CAY30619-10 mg
Supplier:
Size:
10 mg _$$_
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£278.00 Estimated delivery Tue 9 Apr
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

287204-45-9

Purity:

≥98%

Formulation:

A solid

Molecular Weight:

429.3

Alternative Names:

6-(2,6-dichlorophenyl)-2-[(4-fluoro-3-methylphenyl)amino]-8-methyl-pyrido[2,3-d]pyrimidin-7(8h)-one

Product Description:

A Bcr-Abl inhibitor; inhibits wild-type and mutant forms of Bcr-Abl, as well as the p210 isoform (IC50s = 5-48 nM); selective for Bcr-Abl over bFGFR and PDGFR (IC50s = 934 and 1,430 nM, respectively) but also inhibits Src, LCK, KIT, and EGFR (IC50s = 0.8, 1 phase and apoptosis in K562 cells at 50 nM; inhibits constitutive STAT3 DNA-binding activity in and proliferation of MDA-MB-468 breast cancer cells; inhibits proliferation of imatinib-resistant mutant p210 Bcr-AblY253F Ba/F3 cells

Storage Temperature:

-20°C

Details Cat number & supplier Size Price
PD 180970 CAY30619-1 mg · Cayman Chemical
CAY30619-1 mg
Cayman Chemical
1 mg £42.00
1 mg
view
PD 180970 CAY30619-5 mg · Cayman Chemical
CAY30619-5 mg
Cayman Chemical
5 mg £151.00
5 mg
view
N-Oleoyl Glutamine CAY28922-5 mg · Cayman Chemical
CAY28922-5 mg
Cayman Chemical
5 mg £303.00
5 mg
view
Palmitoylcholine (chloride) CAY9003456-10 mg · Cayman Chemical
CAY9003456-10 mg
Cayman Chemical
10 mg £253.00
10 mg
view
N-Oleoyl Glutamine CAY28922-25 mg · Cayman Chemical
CAY28922-25 mg
Cayman Chemical
25 mg £1241.00
25 mg
view
Palmitoylcholine (chloride) CAY9003456-25 mg · Cayman Chemical
CAY9003456-25 mg
Cayman Chemical
25 mg £593.00
25 mg
view
N-Oleoyl Glutamine CAY28922-10 mg · Cayman Chemical
CAY28922-10 mg
Cayman Chemical
10 mg £567.00
10 mg
view
Palmitoylcholine (chloride) CAY9003456-5 mg · Cayman Chemical
CAY9003456-5 mg
Cayman Chemical
5 mg £151.00
5 mg
view
N-Oleoyl Glutamine CAY28922-1 mg · Cayman Chemical
CAY28922-1 mg
Cayman Chemical
1 mg £74.00
1 mg
view
Clinofibrate CAY31109-10 mg · Cayman Chemical
CAY31109-10 mg
Cayman Chemical
10 mg £126.00
10 mg
view