Tranylcypromine (hydrochloride)
Catalogue number:
CAY10010494-1 g
Supplier:
Size:
1 g _$$_
Product is available in:
£152.00
Estimated delivery Wed 1 May
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1986-47-6
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
169.7
Alternative Names:
(1r,2s)-rel-2-phenyl-cyclopropanamine, monohydrochloride, trans-2-phenylcyclopropylamine, 2-pcpa
- Data sheet: View or download
- MSDS: View or download
Product Description:
An irreversible, mechanism-based inhibitor of LSD1 (IC50 = 20.7 µM); irreversibly inhibits MAO-A and MAO-B (IC50s = 2.3 and 0.95 µM, respectively); PCPA inhibits nucleosomal demethylation of H3K4 (IC50 = <2 µM); induces EpiSCs to convert to more undifferentiated state but requires inhibitors of ALK5, MEK, FGFR, and GSK3 for full conversion to pluripotent mESCs; decreases proliferation of neural progenitors in the hippocampal dentate gyrus in adult mice at 10 mg/kg for ten days; decreases the time juvenile rats spend immobile in the forced swim test at 0.4-10 mg/kg
Storage Temperature:
-20°C