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eCF506

Supplier:
Catalogue number:
CAY19959-1 mg
Size:
1 mg
Product is available in:
  • UK
  • Ireland
  • Europe
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  • Rest of World
£37.00 Estimated delivery Fri 18 Jun
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An inhibitor of Src kinases (IC50s = 50 = 479 nM), as well as KIT, mTOR, PDGFRα, and RET (IC50s = >100 µM for all); completely inhibits Src and FAK phosphorylation at 100 nM; inhibits proliferation of MCF-7 cells (EC50 = 9 nM); reduces levels of activated Src kinase in tumor tissue in an HCT116 mouse xenograft model at 50 mg/kg per day

Product Type:

Biochemicals

CAS Number:

1914078-41-3

Alternative Names:

n-[4-[4-amino-1-[2-[4-(dimethylamino)-1-piperidinyl]ethyl]-1h-pyrazolo[3,4-d]pyrimidin-3-yl]-2-methoxyphenyl]-carbamic acid, 1,1-dimethylethyl ester

Storage Temp:

-20°C

Formulation:

A crystalline solid

Compound Purity:

≥98%

UNSPSC Code:

12352200

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