£48.00
Estimated delivery Wed 1 May
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
154554-41-3
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
283.3
Alternative Names:
6-(2-fluorophenyl)-1,3-dioxolo[4,5-g]quinolin-8(5h)-one, nsc 656158
- Data sheet: View or download
- MSDS: View or download
Product Description:
An inhibitor of tubulin polymerization (IC50 = 0.68 µM); inhibits chochicine tubulin binding at 5 µM; inhibits the growth of K562, NCI H226, HCT116, OVCAR-3, RXF 393L, SK-MEL-5, SF-268, and SF-295 cancer cells (mean GI50 = 130 nM); induces apoptosis in HA22T hepatocellular carcinoma cells; reduces tumor volume and increases survival in an HA22T mouse xenograft model at 10 mg/kg
Storage Temperature:
-20°C