CAIX Inhibitor S4
Catalogue number:
CAY31119-10 mg
Supplier:
Size:
10 mg _$$_
Product is available in:
£186.00
Estimated delivery Wed 1 May
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1330061-67-0
Purity:
≥98%
Formulation:
A solid
Molecular Weight:
335.4
Alternative Names:
sulfamic acid, 4-[[[(3,5-dimethylphenyl)amino]carbonyl]amino]phenyl ester
- Data sheet: View or download
- MSDS: View or download
Product Description:
A CAIX inhibitor (Ki = 0.007 µM for the recombinant human enzyme); selective for CAIX over CAI and CAII but does inhibit CAXII (Kis = 5.6, 0.55, and 0.002 µM, respectively); inhibits proliferation of HT-29 and MDA-MB-231, but not HCT116, cancer cells under anoxic conditions (IC50s = 20, 481, and >1,000 µM, respectively); reduces the number of lung metastases, but not primary tumor growth, in an MDA-MB-231 mouse xenograft model at 10 mg/kg
Storage Temperature:
-20°C