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YS-49

Catalogue number:
CAY30970-1 mg
Supplier:
Size:
1 mg _$$_
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£64.00 Estimated delivery Tue 30 Apr
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

132836-42-1

Purity:

≥98%

Formulation:

A crystalline solid

Molecular Weight:

386.3

Alternative Names:

1,2,3,4-tetrahydro-1-(1-naphthalenylmethyl)-6,7-isoquinolinediol, monohydrobromide

Product Description:

A platelet aggregation inhibitor; inhibits ADP-, collagen-, or epinephrine-induced platelet aggregation in isolated human platelets (IC50s = 730, 92, and 3.4 µM, respectively); inhibits arachidonic acid-induced platelet aggregation and TXA2 production in isolated rat platelets (IC50s = 3.3 and 32.8 µM, respectively); reduces LPS-induced contractions in isolated endothelium-denuded rat aortic strips in a concentration-dependent manner; decreases thrombus weight in a rat model of arterio-venous shunt thrombosis at 50 mg/kg; increases survival in a mouse model of septicemia induced by LPS at 10 and 20 mg/kg

Storage Temperature:

-20°C

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