£247.00
Estimated delivery Tue 9 Apr
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1147-56-4
Purity:
≥98%
Formulation:
A solid
Molecular Weight:
255.3
Alternative Names:
1-[2-(2-thiazolyl)diazenyl]-2-naphthalenol, nsc 139021
Product Description:
An ERG inhibitor (IC50 = 315 nM); inhibits proliferation of ERG-expressing VCaP prostate, COLO 320 colon, and KG-1 and MOLT-4 leukemia cancer cells (IC50s = 30-400 nM) but LNCaP, LAPC4, and MDA PCa 2b prostate cancer and HUVECs, which do not express ERG (IC50s = >10 µM for all); reduces tumor growth in a VCaP mouse xenograft model at 100 and 150 mg/kg
Storage Temperature:
-20°C