£374.00
Estimated delivery Tue 30 Apr
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1031206-36-6
Purity:
≥98%
Formulation:
A solid
Molecular Weight:
296.3
Alternative Names:
(3e)-2,3-dihydro-3-[(3-hydroxy-4-methoxyphenyl)methylene]-6-methyl-4h-1-benzopyran-4-one
- Data sheet: View or download
- MSDS: View or download
Product Description:
An anti-choroidal neovascularization agent; inhibits proliferation of NIH3T3 mouse and IMR-90 human fibroblasts (IC50s = 0.5-3 µM), as well as in a panel of eight human cancer cell lines (IC50s = 0.3-3 µM); decreases migration of THP-1 macrophages in wound healing and chamber assays at 10 µM; inhibits VEGF-induced blood vessel formation in a MatrigelTM plug assay in mice at 20 µg/animal; reduces ocular leakage, as well as cellular proliferation and infiltration in a rat model of laser-induced choroidal neovascularization at 100 µg/eye
Storage Temperature:
-20°C