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IMS 2186

Supplier:
Catalogue number:
CAY31157-10 mg
Size:
10 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£132.00 Estimated delivery Thu 1 Jul
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An anti-choroidal neovascularisation agent; inhibits proliferation of NIH3T3 mouse and IMR-90 human fibroblasts (IC50s = 0.5-3 µM), as well as in a panel of eight human cancer cell lines (IC50s = 0.3-3 µM); decreases migration of THP-1 macrophages in wound healing and chamber assays at 10 µM; inhibits VEGF-induced blood vessel formation in a MatrigelTM plug assay in mice at 20 µg/animal; reduces ocular leakage, as well as cellular proliferation and infiltration in a rat model of laser-induced choroidal neovascularisation at 100 µg/eye

Product Type:

Biochemicals

CAS Number:

1031206-36-6

Alternative Names:

(3e)-2,3-dihydro-3-[(3-hydroxy-4-methoxyphenyl)methylene]-6-methyl-4h-1-benzopyran-4-one

Storage Temp:

-20°C

Formulation:

A solid

Compound Purity:

≥98%

UNSPSC Code:

12352200

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