£89.00
Estimated delivery Tue 9 Apr
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1279713-77-7
Purity:
≥98%
Formulation:
A solid
Molecular Weight:
377.8
Alternative Names:
n-[(3-chloro-6-fluorobenzo[b]thien-2-yl)carbonyl]-d-phenylalanine
- Data sheet: View or download
- MSDS: View or download
Product Description:
A TLR3 antagonist (IC50 = 3.44 µM); selective for TLR3 over TLR4, TLR2/6, TLR1/2, and TLR7 at 27 µM; inhibits dsRNA binding to TLR3 (Ki = 2.96 µM in a fluorescence anisotropy assay); decreases poly(I:C)-induced production of TNF-α and IL-1β in RAW 264.7 cells at 27 µM
Storage Temperature:
-20°C