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Sample collection and preservation

DNA/RNA Shield™ from Zymo Research is a DNA and RNA transport and storage medium for any biological sample. DNA/RNA Shield preserves the genetic integrity and expression profiles of samples at ambient temperatures (no refrigeration or freezing needed) and completely inactivates infectious agents (viruses, bacteria, fungi & parasites).

DNA/RNA Shield is compatible with most DNA and RNA purification kits, meaning nucleic acids can be isolated directly from samples stored in this medium without the need for precipitation or reagent removal.

Nucleic acid stabilisation without cold chain

Nucleic acid stabilisation without cold chain

 Prefilled devices, bulk reagent and customs fills available

Sample type/device
DNA/RNA Shield Reagent
Faecal collection tube
Swab collection tube
Blood collection tube
Saliva collection kit
Lysis tubes
Urine conditioning buffer
Swab samples
Environmental samples
Vector (tissue and insect)

DNA/RNA Shield: complete pathogen inactivation
DNA/RNA Shield has been rigorously tested to ensure its capability to inactive even the toughest of viruses. In an independent study, the virucidal activity was shown to inactivate murine parvovirus1. DNA/RNA Shield abides by the Center for Disease Control’s (CDC) guidelines for pathogen inactivation2.

DNA/ RNA Shield effectively inactivates pathogens. This includes tough-to-lyse microbes or viruses without the need for additional steps, such as heat-treatment, homogenisation, or alcohol sterilisation. DNA/RNA Shield has been rigorously tested to ensure inactivation of pathogens including:

B. subtilis, E. faecalis, E. coli, L. fermentum, L. monocytogenes, M. tuberculosis, P. aeruginosa, S. enterica, S. aureus, S. pneumoniae, X. fastidiosa

Parvovirus, Chikungunya virus , Dengue virus, Ebola virus, Herpes simplex virus-1, Herpes simplex virus-2, Influenza A, Rhinovirus, MERS-coronavirus, West Nile virus 

Yeast & eukaryotes 
C. albicans , C. neoformans , S. cerevisiae , P. malariae

1. Dr. Thraenhart and Dr. Jursch. Virucidal activity of the nucleic acid preservation product “DNA/RNA Shield™” against the murine parvovirus (MVM) at 20 °C. 
2. Guidance on the inactivation or removal of select agents and toxins for future use. Center for Disease Control (CDC)

Microbiomics & metagenomics portfolio
Cambridge Bioscience offers a comprehensive solution for microbiomic and metagenomic research from collection to analyses. See the full range.