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Product types:
Small GTPase Activation Assays, Western blot
Quantibody® Cancer Biomarker Arrays
3D Collagen Matrix Cell Contraction Assay

Assemble DNA Constructs Simply & Efficiently Using The Gibson Assembly® Method

Protease Screening & Profiling

Cambridge Bioscience offers access to a fully defined, flexible profiling and screening service for potential drug inhibitors of protease targets in drug discovery. With the choice of an extensive panel of over 60 target proteases, this service uses highly specific and functional fluorogenic based functional assays with specific substrates to avoid the false positives and negatives generated by other assay formats. Testing formats from regular profiling to miniaturised HTS platform are available.

Benefits of Using the RBC Protease Screening & Profiling Service
• Specific fluorogenic peptide substrate assay for both profiling & low cost HTS
• High quality results
• High sensitivity
• Exceptional reproducibility
• No antibody requirement
• Minimum false positives & negatives
• No intermediate dilution
• Small sample requirement - only nanoliters of compound required

Protease Screening & Profiling Services Available
• Larger scale HTS
• Large scale single dose & duplicate profiling
• IC50 profiling - 10 dose with curve fitting
• Ki determination
• Specific Substrates used
• Custom assay development

Protease Screening Targets
Protease Screening ServiceExample Data
To view an example of data produced by the protease profiling and screening service, please Click Here.

Contact Our Specialists
To discuss a screening project, please contact our experienced team by Clicking Here.
Speak To Our Reaction Biology Specialist Vashu