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Embryonic trophoblast stem embryo medium

Cell Guidance Systems offer a unique medium that supports the development of artificial embryo structures, embryonic trophoblast stem embryos (ETS-embryos), when trophoblast stem cells and embryonic stem cells are cocultured. Optimised for robust and efficient generation of ETS-embryos and using a simple protocol, this medium supports the self-assembly of structures that are observed in the mammalian embryo.

Benefits of using the ETS-embryo medium
• Optimised for robust and efficient generation of ETS-embryos
• Provides a unique cell culturing environment
• Supports selfassembly of structures observed in the mammalian embryo
• Simple and easy to follow protocol
• Functionally tested

The lead researchers at Cambridge University talk to Cell Guidance Systems about artificial ETS-embryos

Embryo Development

A series of images showing the development of ETS embryos over a period of five days. Trophoblast-derived cells are stained with a DNA-marker only (blue) and ES-derived cells stained with embryonic marker OCT4 (red).

Embryonic Cells expressing GFP & cherry histone

ESC cells expressing GFP and cherry histone used to highlight the embryonic cells in an ETS-embryo.

Applications
• Improving efficiency of transgenic animal generation
• Tissue and organ creation for stem cell research

Material available for download
ETS-embryo medium brochure
ETS-embryo medium user guide

ETS-embryo medium citations

For more information or a quotation, please contact our Cell Guidance Systems specialist.