The Naveni in situ proximity ligation technology enables visualisation of protein-protein interactions, post-translational modifications or extremely low abundant proteins in cultured cells, fresh-frozen and FFPE samples. The technology uses two primary antibodies to achieve clear detection of proteins with increased specificity and excellent consistency in staining.
Find out more about Naveni proximity ligation technology
Benefits of using the NaveniFlex kits
• Clear target detection
• Consistency in staining
• Simple protocol based on secondary detection using Navenibodies
• Compatible with traditional in situ equipment and workflows
• Sensitive fluorescent readout
• Excellent reproducibility
• Possibility to detect extremely low abundant proteins
• Detection of protein-protein interactions
• Specific detection of post-translational modifications, also with the use of pan-specific antibodies
• Each kit contains Ato488, TEX615 and Atto647N fluorophores
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Left: NaveniFlex MR was used for the detection of protein interaction of beta-catenin and e-cadherin in MCF7 cells using Atto647N fluorophore. Right: NaveniFlex MR was used for the detection of protein interaction of beta-catenin and e-cadherin in human skin tissue using ATTO488 fluorophore.
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Left: NaveniFlex MM was used for the detection of CA125f in CA-125, 5 + Control Slide, (Sigma Aldrich) using TEX615 fluorophore. Right: NaveniFlex MR was used for the detection of protein interaction of chromatin interactions (histone H3) with the nuclear lamina (lamin-B1) in BT474 (breast cancer cells) using TEX615 fluorophore.
Material available for download
NaveniFlex flyer
Application note: Navigating chromatin organisation with NaveniFlex
Frequently asked questions
Products
Note: product availability depends on country - see product detail page.
Details | Cat number & supplier | Size | Price |
NaveniFlex 100 MR NF.MR.100 · Navinci Diagnostics AB | NF.MR.100 Navinci Diagnostics AB |
100 reactions |
£1273.00
100 reactions
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NaveniFlex 100 MM NF.MM.100 · Navinci Diagnostics AB | NF.MM.100 Navinci Diagnostics AB |
100 reactions |
£1273.00
100 reactions
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NaveniFlex 100 RR NF.RR.100 · Navinci Diagnostics AB | NF.RR.100 Navinci Diagnostics AB |
100 reactions |
£1273.00
100 reactions
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NaveniFlex 100 GM NF.GM.100 · Navinci Diagnostics AB | NF.GM.100 Navinci Diagnostics AB |
100 reactions |
£1273.00
100 reactions
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NaveniFlex 100 GR NF.GR.100 · Navinci Diagnostics AB | NF.GR.100 Navinci Diagnostics AB |
100 reactions |
£1273.00
100 reactions
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