In-situ proximity ligation: NaveniBright

The Naveni in situ proximity ligation technology from Navinci enables chromagenic visualisation of protein-protein interactions, post-translational modifications or extremely low abundant proteins in cultured cells, fresh-frozen and FFPE samples. The NaveniBright proximity ligation assay kits provide accurate data and precise staining for the visualisation of in-tact tissue morphology using brightfield microscopy proximity ligation assay and are compatible with traditional brightfield immunostaining equipment. 

Find out more about Naveni proximity ligation technology

Benefits of using these NaveniBright kits
• Ideal for detection of low abundant proteins
• Consistency in staining
• Sensitive brightfield proximity ligation assay readouts
• Simple protocol based on secondary detection using Navenibodies
• Detection of protein-protein interactions and post-translational modifications
• Compatible with traditional brightfield microscopy equipment and workflows

Left: Naveni Brightfield AP kit showing the interaction between E-cadherin and β-catenin in skin tissue. Right: Naveni Brightfield AP showing the interaction between Mucin (MUC16) and Mesothelin in ovary cancer tissue with normal ovary tissue.

Left: NaveniBright HRP kit, showing the interaction between E-cadherin and β-catenin on Sebaceous gland in skin tissue. Right: NaveniBright HRP kit, showing Phosphorylated PDGFRβ (pTyr-PDGFRβ) on PDGFBB stimulated Bj-hTERT cells. 

Material available for download
NaveniBright flyer