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Hepatocytes from hiPSCs: Hepatosight-S

The high purity, hiPSC-derived hepatocytes from Nexel, Hepatosight-S®, enable researchers to gather accurate human data for liver characteristics and functions with guaranteed functionality, reproducibility, availability as well as minimum variations between the batches. Developed using a novel method of hiPSC differentiation into functional hepatocytes, Hepatosight-S overcome the limitations of primary cells. 

Benefits of using Hepatosight-S
• No batch-to-batch variations
• Accurate data
• Cost effective

Cytochemical analysis of Hepatosight-S

Hepatosight-S® Cytochemical Analysis

The hepatocytes exhibit expression of (A) glycogen storage (measured by PAS staining), (B) Albumin (measured by immunostaining), (C) albumin (measured by FACS). Hepatosight-S® expresses mature hepatic marker (Albumin) and is a highly pure population of hepatocytes (Albumin = 95%).

Detecting hepatotoxicity (Hepatosight-S vs HepG2 vs hPH)

Detecting hepatotoxicity (Hepatosight®-s vs HepG2 vs hPH

 

Detecting hepatotoxicity (Hepatosight®-s vs HepG2 vs hPH

Detecting hepatotoxicity (Hepatosight®-s vs HepG2 vs hPH

Cell type
Compound 1
Compound 2
Compound 3
Compound 4
HepG2
Non-toxic
Toxic
Non-toxic
Toxic
hPH
Toxic
Non-toxic
Non-toxic
Non-toxic
Hepatosight-S
Toxic
Non-toxic
Non-toxic
Non-toxic

 

Applications
• Hepatotoxicity testing
• Drug discovery
• 3D spheroid culture
• Development of organ-on-a-chip models

Material available for download
Hepatosight-S SDS
Hepatosight-S media and media supplement SDS
Hepatosight-S user guide

Hepatosight-S citations

Products

Note: product availability depends on country - see product detail page.

Details Cat number & supplier Size Price
Hepatosight-S H-002 · Nexel
H-002
Nexel
>10 million cells £1298.00
>10 million cells
view
Hepatosight-M HMS-002 · Nexel
HMS-002
Nexel
120 ml £312.00
120 ml
view