COVID-19 antibodies

We are here to support scientists involved in COVID-19 testing, research and vaccine development. We offer a comprehensive collection of validated antibodies from our specialist antibody manufacturers including Atlas Antibodies, Bethyl Laboratories and Rockland Immunochemicals. These include polyclonal and monoclonal antibodies which target viral proteins from coronaviruses, viral receptors including ACE2 and a broad range of antibodies to detect anti-human IgG, IgM, and IgA, with multiple target specificity, conjugates and formats available for seroconversion assay development.

Coronavirus antibody highlights

1. Anti-SARS-CoV nucleocapsid (N) protein antibody (cat #: 200-401-A50)
The anti-SARS CoV nucleocapsid protein antibody from Rockland Immunochemicals specifically reacts with the SARS-CoV-2 nucleocapsid protein present in patient samples. This antibody has shown immense success in various diagnostic platforms by detecting the SARS-CoV-2 virus in patient specimens and was featured in a recent Nature article: Thao, T.T.N., Labroussaa, F., Ebert, N. et al. Rapid reconstruction of SARS-CoV-2 using a synthetic genomics platform. Nature (2020).

The immunofluorescence microscopy image above shows localisation of SARS-CoV-2 infection in human liver ductal organoids. SARS-CoV-2 N is indicated in red using Rockland’s Anti-SARS CoV Nucleocapsid Antibody, while E-cadherin is in green and DAPI staining of chromatin in blue.

Immunofluorescence of rabbit anti-SARS-CoV nucleocapsid (N) antibody. Tissue: human Liver ductal organoids. Fixation: 4% PFA. Permeabilization: 0.25% Triton X-100. Antigen retrieval: not required. Primary antibody: Rabbit Anti-SARS-CoV (N) Antibody and Mouse Anti-E-Cadhedrin Antibody at 1:500 overnight at 2-8°C. Secondary antibody: Donkey Anti-Rabbit IgG CY3 Conjugated; Donkey Anti-Mouse IgG AlexaFluor 488 Conjugated for 1hr at RT. Nuclear Counterstain: DAPI. Staining showing Mock and Infected tissue: SARS-CoV Red signal, E-Cadhedrin green signal, with DAPI (blue) nuclear counterstain. [Zhao et al. (2020)]

2. SARS-CoV membrane protein antibody (cat #: 100-401-A55)

Immunofluorescence microscopy using Rockland's anti-SARS-CoV Membrane protein antibody, 6-h post infection Vero-E6 cells. For detection Cy3 conjugated Goat-anti-Rabbit IgG MX (611-104-122) was used. Personal Communication, Eric Snijder, Leiden University Medical Center, Leiden, Netherlands.

ACE antibodies

1. Monoclonal antibody against human ACE2 (Cat #: AMAb91262)

Immunohistochemical staining of human duodenum shows strong immunoreactivity in apical membranes of glandular cells.

2. ACE2 (human) Monoclonal Antibody (Clone AC18F) (Cat #: CAY30582-50 ug & CAY30582-100 ug)

Cambridge Bioscience antibody guarantee
We offer a full guarantee that our antibodies will work in the applications and species stated on the datasheet. If our antibodies do not fulfil this promise, we will not only refund your purchase price but also give you 50 percent off the list price of any of our alternative antibodies to the same target (if available). Find out more about our antibody guarantee.
 
Listed below are a small number of our COVID-19 related antibodies that are available from our wider selection. If you do not see your required antibody listed, please contact us.