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Product types:
3D Cell Culture ECM Hydrogels - TissueSpec®
TransIT-Lenti
3D Cell Culture ECM Scaffolds - TissueSpec®

Highly effective & efficient in vitro delivery of Cas9 RNP for genome editing in challenging cells

2D cell culture ECM surface coatings - NativeCoat™

2D cell culture ECM surface coatings - NativeCoat™

NativeCoat™ is a solubilised, tissue-specific extracellular matrix with native biochemical (porcine) cell composition to maintain phenotype in 2D cell culture. Demonstrating consistent lot-to-lot composition, NativeCoat™ contains the full milieu of proteins and growth factors to recapitulate the native cell environment in vitro to enable increased cell attachment, viability and proliferation as well as enhanced function and activation of signalling pathways.

Benefits of using NativeCoat™
• Contains tissue-specific ECM components
• Lot-to-lot consistency
• Easy-to-use

Sinusoidal endothelial cell viability

Primary human liver sinusoidal endothelial cells cultured in microfluidic channels exhibited uncontrolled outgrowth and loss of viability after 7 days with no coating. In contrast, coating channels with NativeCoat™ Liver ECM supported controlled growth and viability of primary liver sinusoidal endothelial cells for 7 days

Primary human liver sinusoidal endothelial cells cultured in microfluidic channels exhibited uncontrolled outgrowth and loss of viability after 7 days with no coating. In contrast, coating channels with NativeCoat™ Liver ECM supported controlled growth and viability of primary liver sinusoidal endothelial cells for 7 days.

Applications
• Cell culture
• Cancer research
• Stem cell research
• Tissue engineering
• Clinical applications
• Drug screening
• Organ-on-a-chip

NativeCoat™ Citations

Material available for download
NativeCoat™ 2D ECM Surface Coatings Manual

Custom projects
Standard NativeCoat™ ECM products are derived from porcine tissues. However, the Xylyx platform technology allows matrix isolation from different tissue sources, including human tissues according to specific requests. Discuss a custom project with our Xylyx specialist.

Products

Note: availability depends on country - see product detail page.

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Applications: 2D Cell Culture, Microphysiologic Systems, Organs-on-a-Chip, High Throughput Drug Screening, Disease Modeling, Cancer Research, Regenerative Medicine
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Applications: 2D Cell Culture, Microphysiologic Systems, Organs-on-a-Chip, High Throughput Drug Screening, Disease Modeling, Cancer Research, Regenerative Medicine
View product detail
Applications: 2D Cell Culture, Microphysiologic Systems, Organs-on-a-Chip, High Throughput Drug Screening, Disease Modeling, Cancer Research, Regenerative Medicine
View product detail
Applications: 2D Cell Culture, Microphysiologic Systems, Organs-on-a-Chip, High Throughput Drug Screening, Disease Modeling, Cancer Research, Regenerative Medicine
View product detail
Applications: 2D Cell Culture, Microphysiologic Systems, Organs-on-a-Chip, High Throughput Drug Screening, Disease Modeling, Cancer Research, Regenerative Medicine
View product detail
Applications: 2D Cell Culture, Microphysiologic Systems, Organs-on-a-Chip, High Throughput Drug Screening, Disease Modeling, Cancer Research, Regenerative Medicine
View product detail
Applications: 2D Cell Culture, Microphysiologic Systems, Organs-on-a-Chip, High Throughput Drug Screening, Disease Modeling, Cancer Research, Regenerative Medicine
View product detail
Applications: 2D Cell Culture, Microphysiologic Systems, Organs-on-a-Chip, High Throughput Drug Screening, Disease Modeling, Cancer Research, Regenerative Medicine
View product detail
Applications: 2D Cell Culture, Microphysiologic Systems, Organs-on-a-Chip, High Throughput Drug Screening, Disease Modeling, Cancer Research, Regenerative Medicine
View product detail
Applications: 2D Cell Culture, Microphysiologic Systems, Organs-on-a-Chip, High Throughput Drug Screening, Disease Modeling, Cancer Research, Regenerative Medicine
View product detail
Applications: 2D Cell Culture, Microphysiologic Systems, Organs-on-a-Chip, High Throughput Drug Screening, Disease Modeling, Cancer Research, Regenerative Medicine
View product detail
Applications: 2D Cell Culture, Microphysiologic Systems, Organs-on-a-Chip, High Throughput Drug Screening, Disease Modeling, Cancer Research, Regenerative Medicine
View product detail
Applications: 2D Cell Culture, Microphysiologic Systems, Organs-on-a-Chip, High Throughput Drug Screening, Disease Modeling, Cancer Research, Regenerative Medicine
View product detail
Applications: 2D Cell Culture, Microphysiologic Systems, Organs-on-a-Chip, High Throughput Drug Screening, Disease Modeling, Cancer Research, Regenerative Medicine

Speak To Our Xylyx Specialist Doaa

Xylyx - Tissue-Specific ECM Substrates For 2D & 3D Cell Culture