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Recombinant epigenetic regulatory proteins

This large collection of high purity recombinant epigenetic regulatory proteins from Reaction Biology Corporation are for use in the study of heritable phenotypic changes resulting from modifications in chromosomes, especially histone protein modifications, which affect gene activity and expression. This portfolio comprises methyltransferases and demethylases, methyltransferase substrates, reader domains, histone deacetylases and acetylases (HDAC), PARP proteins, NAD(P)H dehydrogenase quinone proteins (NQOs – QRs), histone demethylases and epigenetic inhibitors

Benefits of using these recombinant epigenetic regulatory proteins
• Each protein is functionally tested
• High purity
• Largest collection of methyltransferase proteins and reader domain proteins
• Broadest range of proteins for epigenetic assays

Epigenetics proteins SDS-PAGE

Methylation activity of ASH1L with various types of nucleosomes

Methylation Activity of ASH1L With Various Types Of Nucleosomes

Assays were performed with a scintillation/filter plate assay. 100 nM or 60 nM ASH1L was incubated 60 min, 30⁰C with HeLa Oligonucleosomes (catalogue number HMT-35-130), HeLa Mononucleosomes (catalogue number HMT-35-123), Chicken Oligonucleosomes (catalogue number HMT-35-177), Chicken Mononucleosomes (catalogue number HMT-35-179), Recombinant Tetranucleosomes (catalogue number HMT-15-367) and Recombinant Mononucleosomes (catalogue number HMT-15-369); 0.05 mg/mL as [DNA]) and 3.25 µM SAM (1:1.6[3H]-SAM:unlabelled).

Please find below a small selection of recombinant epigenetic regulatory proteins from our large portfolio.
If you can’t find the protein you are looking for, contact our reaction biology specialist here.

Products

Note: product availability depends on country - see product detail page.

Details Cat number & supplier Size Price
ASH1L- (BRD) (GST) RD-11-240 · Reaction Biology Corporation
RD-11-240
Reaction Biology Corporation
100 µg £384.00
100 µg
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BIX-01294 EI-HMT-003 · Reaction Biology Corporation
EI-HMT-003
Reaction Biology Corporation
5 mg £118.00
5 mg
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HDAC1 KDA-21-365 · Reaction Biology Corporation
KDA-21-365
Reaction Biology Corporation
50 µg £546.00
50 µg
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ASH1L (His) Methyltransferase HMT-11-376 · Reaction Biology Corporation
HMT-11-376
Reaction Biology Corporation
50 µg £450.00
50 µg
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LSD1 (His) PDM-11-350 · Reaction Biology Corporation
PDM-11-350
Reaction Biology Corporation
50 µg £486.00
50 µg
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CoRest PDM-11-332 · Reaction Biology Corporation
PDM-11-332
Reaction Biology Corporation
50 µg £450.00
50 µg
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PARP2 (GST) PAR-21-347 · Reaction Biology Corporation
PAR-21-347
Reaction Biology Corporation
20 µg £558.00
20 µg
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PARP1 (His) PAR-21-346 · Reaction Biology Corporation
PAR-21-346
Reaction Biology Corporation
20 µg £558.00
20 µg
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NQO2 NQO-11-312 · Reaction Biology Corporation
NQO-11-312
Reaction Biology Corporation
50 µg £450.00
50 µg
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ATAD2 (His) RD-11-251 · Reaction Biology Corporation
RD-11-251
Reaction Biology Corporation
100 µg £384.00
100 µg
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Sinefungin EI-HMT-005 · Reaction Biology Corporation
EI-HMT-005
Reaction Biology Corporation
1 mg £90.00
1 mg
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