CD4+ & CD8+ T-cell stimulating peptide pools: PepMix

The PepMix™ range of high quality peptide pools for the in vitro stimulation of CD4+ and CD8+ T-cell responses spans more than 100 antigens or mixed epitope pools, including tumour associated and infectious disease antigens. The PepMix peptide pools are created by antigenic protein sequences being divided into overlapping peptides, chemically synthesised and then analysed to comply with the requirements of T-cell assays.

Benefits of using the PepMix Peptide Pools
• Simultaneous CD4 and CD8 response detection in a single sample (CEF pools: CD8 only)
• Better or equivalent T-cell response stimulation compared to whole protein antigens
• Improved and easier T-cell response detection in stored blood and PBMCs compared to whole protein antigens
• Reliable quality control and quality assurance
• High batch-to-batch reproducibility
• Prolonged shelf life when stored freeze-dried
• Pooled and aliquoted according to ISO 9001:2008 and GCLP regulations

Testimonials
"I have used JPT's peptide pools (PepMix) for years now, with great satisfaction! First CMV derived peptides and now also EBV. So far, we have published data in one publication and plan several more in the near future."
Anna Karin Lidehaell, Uppsala University, Clin. Immunol., Uppsala, Sweden

PepMix Peptide Pools applications
• Vaccine efficacy testing
• Antigen specific T-cell response measurement
• Antigen-specific T-cell responses correlation with immune status
• Antigen specific T-lymphocyte generation for adoptive immunotherapy
• T-lymphocyte epitope discovery

PepMix Algorithm

PepMix Peptide Pool Range
1. Positive and negative control pools
Including CEF, CEFT and EF Pools, HCMV (pp65, IE-1...), Human Actin
2. Infectious disease pools
Including EBV (EBNAs, BLZF1...), BKV (VP1, largeT...), Adenovirus, HPV, HIV, Influenza and many more
3. Tumour associated antigens
Including melanoma, prostate and breast cancer, glioma, gastric cancer, testicular/ovarian cancer, Wilms tumour and many more

Material available for download
Cytomegalovirus protein spanning PepMix peptide pools to discover changes in T cell immunity in the aging population
T cell therapy for viral infections after hematopoietic stem cell transplan t
Qualification and use of peptide libraries for clinical trial immunomonitoring

PepMix citations

Products

Note: product availability depends on country - see product detail page.

Details	Cat number & supplier	Size	Price
PepMix Human (Actin) PM-ACTS · JPT Peptide Technologies	PM-ACTS JPT Peptide Technologies	15 nmol (~25 µg) per peptide	£568.00 15 nmol (~25 µg) per peptide view
PepMix Human (CEA) PM-CEA · JPT Peptide Technologies	PM-CEA JPT Peptide Technologies	15 nmol (~25 µg) per peptide	£748.00 15 nmol (~25 µg) per peptide view
PepMix Human (Cyclin-B1) PM-CYC_B1 · JPT Peptide Technologies	PM-CYC_B1 JPT Peptide Technologies	15 nmol (~25 µg) per peptide	£696.00 15 nmol (~25 µg) per peptide view
PepMix Human (ErbB2_ECD) PM-ERB_ECD · JPT Peptide Technologies	PM-ERB_ECD JPT Peptide Technologies	15 nmol (~25 µg) per peptide	£748.00 15 nmol (~25 µg) per peptide view
PepMix Human (ErbB2_ICD) PM-ERB_ICD · JPT Peptide Technologies	PM-ERB_ICD JPT Peptide Technologies	15 nmol (~25 µg) per peptide	£696.00 15 nmol (~25 µg) per peptide view
PepMix Human (HLA classI Ig-like C1 type domain) PM-C1 · JPT Peptide Technologies	PM-C1 JPT Peptide Technologies	15 nmol (~25 µg) per peptide	£598.00 15 nmol (~25 µg) per peptide view
PepMix Human (MAGEA1) PM-MAGEA1 · JPT Peptide Technologies	PM-MAGEA1 JPT Peptide Technologies	15 nmol (~25 µg) per peptide	£645.00 15 nmol (~25 µg) per peptide view
PepMix Human (MAGEA3) PM-MAGEA3 · JPT Peptide Technologies	PM-MAGEA3 JPT Peptide Technologies	15 nmol (~25 µg) per peptide	£645.00 15 nmol (~25 µg) per peptide view
PepMix Human (MAGEA4) PM-MAGEA4 · JPT Peptide Technologies	PM-MAGEA4 JPT Peptide Technologies	15 nmol (~25 µg) per peptide	£645.00 15 nmol (~25 µg) per peptide view
PepMix Human (Mammaglobin A) PM-MamA · JPT Peptide Technologies	PM-MamA JPT Peptide Technologies	15 nmol (~25 µg) per peptide	£598.00 15 nmol (~25 µg) per peptide view
PepMix Human (Melan-A/MART-1) PM-MelA · JPT Peptide Technologies	PM-MelA JPT Peptide Technologies	15 nmol (~25 µg) per peptide	£598.00 15 nmol (~25 µg) per peptide view
PepMix Human (Melanocyte protein Pmel 17 gp100) PM-GP100 · JPT Peptide Technologies	PM-GP100 JPT Peptide Technologies	15 nmol (~25 µg) per peptide	£748.00 15 nmol (~25 µg) per peptide view
PepMix Human (Metalloreductase STEAP1) PM-STEAP1 · JPT Peptide Technologies	PM-STEAP1 JPT Peptide Technologies	15 nmol (~25 µg) per peptide	£645.00 15 nmol (~25 µg) per peptide view
PepMix Human (MOG) PM-MOG · JPT Peptide Technologies	PM-MOG JPT Peptide Technologies	15 nmol (~25 µg) per peptide	£598.00 15 nmol (~25 µg) per peptide view
PepMix Human (Myc protein) PM-cMyc · JPT Peptide Technologies	PM-cMyc JPT Peptide Technologies	15 nmol (~25 µg) per peptide	£696.00 15 nmol (~25 µg) per peptide view

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