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Ethically Sourced & Fully Traceable Human Hepatitis & HIV Biospecimens

Stem Cell Reprogramming Cocktail Sets

Unique Cryopreservation Media

Highly effective & efficient in vitro delivery of Cas9 RNP for genome editing in challenging cells

Stem cell reprogramming cocktail sets

Stem cell reprogramming cocktail sets

StemBoost™ sets are sterile filtered cocktail solutions (1000x, in DMSO) which include those designed to enhance the reprogramming efficiency of human somatic cells to induced pluripotent stem cells (iPSCs), a cocktail set for the maintenance of pluripotency in embryonic stem cells (ESCs) and also one to enhance the induction of neuronal cells from human  fibroblasts. Please see below for further information.

1. StemBoost™ Reprogramming Cocktail Set I
StemBoost™ reprogramming cocktail set I enhances the reprogramming efficiency of human somatic cells to iPSCs. The four products in the cocktail are:
• A83-1 - an ALK5 kinase inhibitor
• CHIR99021 - a selective GSK-3β inhibitor
• PD0325901 - a MEK inhibitor
• Thiazovivin - an enhancer of hESCs survival

2. StemBoost™ Reprogramming Cocktail Set II
StemBoost™ reprogramming cocktail set II enhances the reprogramming efficiency of human somatic cells to iPSCs. The four products in the cocktail are:
• CHIR99021 - a selective GSK-3β inhibitor
• PD0325901 - a MEK inhibitor
• SB-431542 - an ALK5 kinase inhibitor
• Thiazovivin - an enhancer of hESCs survival

3. StemBoost™ 2i-Reprogramming Cocktail Set
The StemBoost™ 2i-reprogramming cocktail set enhances the reprogramming efficiency of human somatic cells to iPSCs. The two products in the cocktail are:
• CHIR99021 - GSK-3β inhibitor
• PD0325901 - MEK inhibitor

4. StemBoost™ YPAC Cocktail Set
The StemBoost™ YPAC cocktail set is useful for maintaining pluripotency in ESCs. The four signalling inhibitors in the cocktail are:
• Y-27632 - a ROCK inhibitor
• PD0325901 - a MEK inhibitor
• A83-01 - an ALK5 inhibitor
• CHIR99021 - a GSK-3β inhibitor

5. StemBoost™ Neuronal Cell Induction Cocktail Set
The StemBoost™ neuronal cell induction cocktail set is useful for induction of neuronal cells from human fibroblasts. The seven products in the cocktail are:
• CHIR99021 - GSK 3 inhibitor
• RepSox -TGFβ inhibitor
• Forskolin -cAMP activator
• SP600125 -JNK inhibitor
• Gö6983 -PKC inhibitor
• Y-27632 HCl -ROCK inhibitor
• Valproic Acid Sodium Salt (VPA) -HDAC inhibitor

6. StemBoost™ Nociceptor Induction Cocktail Set
The StemBoost™ nociceptor induction cocktail set is useful for enhancing the induction of neuronal differentiation of hPSCs into nociceptors. The three products in the cocktail are:
• CHIR99021 - GSK-3β inhibitor
• DAPT - γ-Secretase inhibitor
• SU-5402 - FGFR inhibitor

7. StemBoost™ SMAD Signalling Inhibitor Cocktail Set
The StemBoost™ SMAD signalling inhibitor cocktail set useful for inhibiting SMAD signalling and can be used to accelerate hPSCs into nociceptors. The two products included in the cocktail are:
• LDN193189 - BMP inhibitor
• SB-431542 - ALK5 inhibitor

Material available for download
StemBoost™ Reprogramming Cocktail Set I datasheet
StemBoost™ Reprogramming Cocktail Set II datasheet
StemBoost™ 2i-Reprogramming Cocktail Set datasheet
StemBoost™ YPAC Cocktail Set datasheet
StemBoost™ Neuronal Cell Induction Cocktail Set datasheet
StemBoost™ Nociceptor Induction Cocktail Set datasheet
StemBoost™ SMAD Signalling Inhibitor Cocktail Set datasheet

View our stem cell fate regulator sets here

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Structure: https://www.biovision.com/media/catalog/product/pl
Compound Purity: ≥97% by HPLC
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Structure: https://www.biovision.com/media/catalog/product/pl
Compound Purity: ≥97% by HPLC
View product detail
Structure: https://www.biovision.com/media/catalog/product/pl
Compound Purity: ≥97% by HPLC
View product detail
Structure: https://www.biovision.com/media/catalog/product/pl
Compound Purity: ≥97% by HPLC
View product detail
Structure: https://www.biovision.com/media/catalog/product/pl
Compound Purity: ≥97% by HPLC
View product detail
Structure: https://www.biovision.com/media/catalog/product/pl
Compound Purity: ≥97% by HPLC
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