Supplier information: Epigentek

Epigentek is the leading developer and provider of innovative technologies for epigenetic-related products. The company has developed a comprehensive portfolio of more than 400 proprietary products to provide complete and systematic solutions for epigenetics-related research and drug discovery.

MethylFlash™ Hydroxymethylated DNA Quantification Kit
Introductory Offer: 30% Off

The new MethylFlash™  Hydroxymethylated DNA Quantification Kit contains all reagents necessary for the quantification of global DNA hydroxymethylation. Unlike other assays, this kit specifically measures the levels of 5-hydroxymethylcytosine (5-hmC) without cross-reactivity to methylcytosine and unmethylated cytosine.

To mark the release of this ground breaking product, we are offering a introductory 30% discount off this kit.
To find out more, please Click Here.

• Fast procedure, which can be finished within 3 hours.
• One-step colorimetric assay without need for affinity chromatography and Western blotting.
• Included SUMO protein as the positive control allows HDAC1 sumoylation to be quantified.
• Strip microplate format makes the assay flexible: manual or high throughput analysis.
• Reliable and consistent assay conditions

Global DNA hypomethylation has been proposed as a molecular marker in multiple biological processes such as cancer. The Methylamp Global DNA Methylation Quantification Kit uses a unique procedure to quantify global DNA methylation.

• Quick procedure - finish in 4h
• No radioactivity, extraction or chromatography
• Strip microwell format for flexible assay - manual or high throughput

The EpiQuik™ HDAC Activity/Inhibition Assay Kit is a ready-to-use set of essential components needed to measure HDAC activity/inhibition safely and quickly. It is suitable for measuring HDAC activity/inhibition from a broad range of species including mammalian cells/tissues, plants, and bacteria

• Finish within 3 hours
• Colorimetric assay: no need for radioactivity, extraction, or chromatography
• Directly measure HDAC activity and inhibition, without using lysyl endpeptidase, thereby avoiding its false inhibitory effect on HDACs
• Strip microplate format

Dramatically cut down the time taken for your ChIP procedure

• < 5 hour procedure
• Strip microwell format for flexible assay - manual or high throughput
• Columns for DNA purification are included
• Compatible with all DNA amplification-based approaches

Epigentek have released a new, rapid and convenient DNA Modfication Kit for epigenetic studies. Traditionally conversion of unmethylated cytosine to uracil required an initial DNA denaturation step prior to bisulphite treatment. However Epigentek has devised new technology to allow denaturation and bisulphite conversion to occur simultaneously whilst boosting levels of efficiency and accuracy.

Advantages:

• Fast: Protocol takes 30 minutes
• Efficient: >99.9% of DNA converted
• Protective: 90% of DNA degradation blocked
• Sensitive: Works with as little as 0.2ng DNA

Please click here for more information.