Montelukast (sodium salt)
Catalogue number:
CAY10008318-50 mg
Supplier:
Size:
50 mg _$$_
Product is available in:
£102.00
Estimated delivery Wed 29 May
Shipping is calculated in checkout
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
151767-02-1
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
608.2
Alternative Names:
1-[[[(1r)-1-[3-(1e)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]-methyl]-cyclopropaneacetic acid, monosodium salt, mk-476
- Data sheet: View or download
- MSDS: View or download
Product Description:
A CysLT1 receptor antagonist (IC50 = 4.9 nM in HEK293 cell membranes expressing the human receptor); selective for CysLT1 over CysLT2 receptors (IC50 = >10,000 nM in COS-7 cell membranes expressing the human receptor); inhibits LTD4-induced bronchoconstriction in anesthetized guinea pigs (ED50 = 69 nmol/kg, p.o.); inhibits ovalbumin-induced airway hyperresponsiveness and increases in the number of total cells and eosinophils in BALF in a mouse model of allergic asthma at 3 and 10 mg/kg
Storage Temperature:
-20°C
