Zafirlukast
Catalogue number:
CAY10008282-500 mg
Supplier:
Size:
500 mg _$$_
Product is available in:
£772.00
Estimated delivery Wed 15 May
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
107753-78-6
Purity:
≥97%
Formulation:
A crystalline solid
Molecular Weight:
575.7
Alternative Names:
[3-[[2-methoxy-4-[[[(2-methylphenyl)sulfonyl]amino]carbonyl]phenyl]methyl]-1-methyl-1h-indol-5-yl]-carbamic acid, cyclopentyl ester
- Data sheet: View or download
- MSDS: View or download
Product Description:
A CysLT1 receptor antagonist (IC50 = 0.014 µM in a cell-based calcium mobilization assay); selective for CysLT1 over CysLT2 receptors (IC50 = 58 µM); inhibits LTD4-induced mucus secretion in isolated guinea pig trachea (IC50 = 0.6 µM); inhibits ovalbumin-induced increases in tracheal mucus secretion in ovalbumin-sensitized guinea pigs by 65% at 5 µM; inhibits LTD4-induced bronchoconstriction in anesthetized guinea pigs (ED50 = 61 nmol/kg, i.v.)
Storage Temperature:
-20°C
