£41.00
Estimated delivery Wed 15 May
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
479413-70-2
Purity:
>98%
Formulation:
A crystalline solid
Molecular Weight:
392.6
Alternative Names:
12-[[(tricyclo[3.3.1.13,7]dec-1-ylamino)carbonyl]amino]-dodecanoic acid
- Data sheet: View or download
- MSDS: View or download
Product Description:
AUDA is an inhibitor of sEH exhibiting IC50 values of 18 and 69 nM for the mouse and human enzymes, respectively.{14064} In angiotensin-infused rats, a dose of 25 mg/l AUDA administered in drinking water decreased mean arterial blood pressure from 161 ± 4 mmHg to 140 ± 5 mmHg. This hypotensive effect was accompanied by an increase in urinary epoxide-to-diol ratios.{14065} AUDA activates PPARα 3-fold at a concentration of 10 µM but exhibits no affect on PPAR.delta. or PPARγ.{13447}
Storage Temperature:
-20°C
