£20.00
Estimated delivery Wed 29 May
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
486-66-8
Purity:
≥95%
Formulation:
A crystalline solid
Molecular Weight:
254.2
Alternative Names:
7-hydroxy-3-(4-hydroxyphenyl)-4h-1-benzopyran-4-one
- Data sheet: View or download
- MSDS: View or download
Product Description:
An isoflavone; binds to ERβ (Ki = 2.8 µM) but not ERα up to 1 mM; estrogenic in vitro, increasing ERE-mediated gene transcription via ERβ (EC50 = 2.8 µM); an inhibitor of CAVII and CAXII (Kis = 4.2 and 56 nM, respectively) and selective for them over CAI, II, and IV (Kis = >10,000, >10,000, and 718.7 nM, respectively); reduces tumor growth in a PC3 prostate cancer mouse orthtopic model at 50 mg/kg per day
Storage Temperature:
-20°C