Rat MOG recombinant protein (1-125) [Cat# AS-55152] is able to induces autoantibody production and relapsing-remitting neurological disease causing extensive plaque-like demyelination. Autoantibody response to rat MOG (1-125) has been observed in induced experimental autoimmune encephalomyelitis (EAE) in dark agouti (DA) and Lewis rats, C57/BL6 and SJL mice, and common marmoset.
The SensoLyte® Anti-Rat MOG (1-125) IgG Quantitative ELISA Kit provides a convenient quantitative assay for anti-rat MOG (1-125) autoantibody. This colorimetric assay is useful to researchers for determining the amount of anti-rat MOG (1-125) antibody present, and can help provide information on the role it plays in the development and treatment of EAE, an animal model for multiple sclerosis pathogenesis.
4°C