£167.00
Estimated delivery Thu 25 Apr
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CAS Number:
131580-10-4
Purity:
Peak Area by HPLC ≥95%
Molecular Weight:
1955.1
Product Description:
Proteins interactions with reactive oxygen agents may result in covalent modifications of amino acid residues in proteins, formation of protein-protein cross-linkages and oxidation of the protein backbone resulting in protein fragmentation. Oxidation targets for Aβ(1-16) are the histidine residues coordinated to the metal ions. Copper is bound to Aβ in senile plaque of Alzheimer’s disease with Aβ (1-16) taking part in the coordination of the Cu2+ ions. Cu2+ and Zn2+ are linked with the neurotoxicity of Aβ and free radical damage.
Storage Temperature:
-20°C