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Beta-Amyloid (1-16), Human - ANA24225 - 1 mg - AnaSpec - proteins & peptides

Beta-Amyloid (1-16), Human
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Size: 1 mg
£109.00
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Catalogue number:
ANA24225
Name:
Beta-Amyloid (1-16), Human
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Proteins interactions with reactive oxygen agents may result in covalent modifications of amino acid residues in proteins, formation of protein-protein cross-linkages and oxidation of the protein backbone resulting in protein fragmentation. Oxidation targets for Aß(1-16) are the histidine residues coordinated to the metal ions. Copper is bound to Aß in senile plaque of Alzheimer’s disease with Aß (1-16) taking part in the coordination of the Cu2+ ions. Cu2+ and Zn2+ are linked with the neurotoxicity of Aß and free radical damage.

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Product Type:
Proteins & Peptides
Alternative Names:
DAEFRHDSGYEVHHQK
Storage Temp:
-20°C
Molecular Weight:
1955
Reference:
Da Silva, GFZ. et al. J. Biol. Chem. 280, 16601 (2005); Kowalik-Jankowska, T. et al. J. Inorg. Biochem. 98, 940 (2004); Kowalik-Jankowska, T. et al. J. Inorg. Biochem. 95, 270 (2003).
UNSPSC Code:
12352202