LDLR Antibody
LDLR Antibody
Catalogue number:
3839-100
Name:
LDLR Antibody
Supplier:
Availability:
Low density lipoprotein receptors (LDLR) are cell surface glycoproteins that regulate LDL cholesterol by scavenging LDL from the blood. LDLR is characterized by a cluster of cysteine-rich class A repeats, EGF-like repeats, the O-linked sugars domain and six YWTD or class B repeats. Mutations in the LDLR gene cause autosomal dominant disease such as familial hypercholesterolemia (FH) and atherosclerosis.
Data sheet:
Applications:
Western blot
Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes mature LDLR (160 kDa), LDLR precursor (120 kDa) and LDLR monomer (~50 kDa).
Product Type:
Antibodies - primary
Species Reactivity:
Human, mouse, rat, bovine, hamster
Immunogen:
Synthetic peptide corresponding to residues surrounding amino acids 850 of human LDLR
Storage Temp:
-20 °C
Accession Number:
P01130
Antibody Host:
Rabbit
Antibody Isotype:
Rabbit IgG
Antibody Type:
Polyclonal
More Info:
Sample Type:
Affinity Purified Antibody
Shelf Life:
12 months
Specifications:
100 µg (0.5 mg/ml) affinity purified rabbit anti-LDLR polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
UNSPSC Code:
12352203
