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JNK Antibody

Catalogue number:
Supplier:
BioVision
Size:
100 µg _$$_
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
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Applications:

Western blot, Immunoprecipitation, Immunohistochemistry

Antibody Host:

Rabbit

Species Reactivity:

Human, mouse, rat

Antibody Isotype:

Rabbit IgG

Antibody Type:

Polyclonal

Immunogen:

Synthetic peptide surrounding amino acid 412 of human JNK-1

Product Description:

The JNK pathway is activated by largely distinct stimuli including inflammatory cytokines (such as TNF-α and IL-1), UV light, inhibitors of protein synthesis and osmotic stress. Activated MEKK1 phosphorylates SEK1 (also known as MKK4), which in turn activates SAPK (also known as JNK). JNK binds tightly to the N-terminal region of c-Jun and ATF-2, and phosphorylates c-Jun at Ser63 and Ser73 and ATF-2 at Thr69 and Thr71.

Storage Temperature:

-20°C

JNK Antibody
JNK Antibody
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