Lamin A Antibody
Catalogue number:
3267-100
Supplier:
BioVision
Size:
100 µg _$$_
Product is available in:
N/A
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This product is no longer available to order.
Applications:
Western blot, Immunohistochemistry
Antibody Host:
Rabbit
Species Reactivity:
Human, mouse, rat
Antibody Isotype:
Rabbit IgG
Antibody Type:
Polyclonal
Immunogen:
Synthetic peptide surrounding amino acid 220 of human Lamin A
- Data sheet: View or download
Product Description:
Lamins are nuclear membrane structural components that are important in maintaining normal cell functions such as cell cycle control, DNA replication and chromatin organization. Lamin A is specifically cleaved by caspase-6 and therefore serves as a marker for caspase-6 activation. During apoptosis the 70 kDa lamin A is cleaved to a large (40-45 kDa) and small (23 kDa) fragment. The cleavage of lamins results in nuclear disregulation and cell death.
Storage Temperature:
-20°C
