Toll-like receptors are a class of proteins that play an important role in innate immunity. They are expressed on the cell surface and endosomal compartments of a range of myeloid cells including dendritic cells and macrophages and elicit a pro-inflammatory response to Pathogen Associated Molecular Patterns (PAMPs). Cambridge Bioscience offers a diverse range of tools for investigating these receptors including antibodies bioactive ligands and stably transfected cells.