Stem Cells

Cambridge Bioscience offers custom stem cell and iPSC services from Sytem Biosciences (SBI). This service offers custom generation of iPSCs from patient samples and other model systems using both viral and nonviral methods, in addition to other stem cell related custom services. We can also offer the generation of iPSC reporter cell lines, perform directed differentiation and build custom lineage reporters.

Features of Custom Stem Cell & iPSC Services
• Choice of retroviral or footprint-free minicircle and PiggyBac based iPSC reprogramming
• Generate disease and patient-specific iPSCs from your own model system
• Retroviral reprogramming using standard Oct4, Sox2, c-Myc, and Klf4 Factors
• iPSC colonies selected based on expected morphology
• AP staining & immunostaining of ESC markers Nanog or Oct4, SSEA3/4 & TRA-1-81 included
• 5 validated iPSC colonies provided for each genotype (>2 x 10⁵ cells/colony)
• Timelines for mouse iPSCs: 2-3 months and human iPSCs: 3-4 months

Examples of patient specific iPS cell lines created at SBI

To request a quote or for more information regarding your custom stem cell and iPSC project, please Click Here