Tel: +44 (0)1223 316 855
life science research products, biological research products, biotechnology
close ...


Supplier:
Product types:
Cell Transformation Assays With No Manual Cell Counting
Comprehensive Epigenetic Profiling and Screening Services
Ion Channel Screening & Profiling Services

Purinergic Receptor Channels

Cambridge Bioscience, through our collaboration with B'SYS, offers access to screening services for the following ionotropic purinergic receptor channel targets:

P2X1
Gene Name: P2RX1
Description: The human P2RX1 gene encodes P2X1, an ionotropic ATP receptor that functions as an ATP- or ADP-activated cation channel, expressed in smooth muscle, platelets and sensory neurons. A P2RX1 mutation has been linked to a severe bleeding disorder arising from impaired ADP-induced platelet aggregation. P2X1 receptors are therapeutic targets in treatment of urinary incontinence and pain.

P2X4
Gene Name: P2RX4
Description: The human P2RX4 gene encodes P2X4, an ionotropic ATP receptor that functions as an ATP-activated cation channel expressed in the CNS, alveolar macrophages, vascular endothelium and airway smooth muscle. P2X4 receptors are therapeutic targets in treatment of neuropathic pain, asthma and heart failure.

P2X7
Gene Name:
P2RX7
Description: The human P2RX7 gene encodes P2X7, an ionotropic ATP receptor that functions as an ATP-activated cation channel expressed in lymphocytes and microglia. P2X7 receptors are therapeutic targets in the treatment of osteoporosis, neuropathic and inflammatory pain and also immune diseases.

Speak to a Specialist
To discuss an ion channel screening project with one of our specialists, please Click Here

Contact Our B'SYS Specialist, Vashu