miRNAs

MicroRNAs (miRNAs) are naturally occurring non-coding small RNAs of 21-23 nucleotides which play an important role in gene-expression regulation. miRNAs have been implicated in many biological processes as well as disease development.

Cambridge Bioscience provides a wide range of tools for microRNA research. This includes kits for the isolation of miRNA and 3’UTR clones and reporters for the study of the interaction of specific miRNA with regulatory gene sequences. The offering also includes the largest collection of premade miRNA precursor clones housed in lentivector and FIV based systems for the over expression of specific miRNAs, a comprehensive collection of premade lentivector based constructs to knock down specific miRNAs and CMV vector based pre-made constructs for the over expression of over 600 human and 400 mouse miRNAs.

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