Manual Cardiac Channel Panel Screening

Conventional manual patch clamp assays provide the most versatile and accurate assessment of drug interactions with cardiac ion channels.

Cambridge Bioscience offers access to manual patch clamp cardiac ion channel panel screening services from ChanTest for the profiling of the most important cardiac ion channels and the comparison of concentration-response parameters.

Features of this Assay
• Gold-standard, functional cell-based ion channel assay
• Quantitative profiling
• Rapid turnaround times - one week (non-GLP) or three weeks (GLP)
• Physiological temperature available for most assays
• Range-finding pre-test available for concentration-response assays
• HPLC concentration-verification available

Optional Assays Available
The following assays can be added to the standard project:
• Dose solution analysis – GLP & non-GLP
• Use-dependence analysis
• Temperature-dependence analysis

Additional Options Available
The following features can be added to the standard project:
• Additional copies of final report
• Copies of solution worksheets & data-collection forms
• Integrated risk assessment summary – dose-response, repolarization and in vivo data compiled in one report

Request A No Obligation Quote
To discuss a manual patch clamp cardiac ion channel panel screening project, please contact our experienced team by Clicking Here