Histamine Receptors
Cambridge Bioscience, through our collaboration with ChanTest, offers access to GPCR screening and profiling services to the following histamine receptor targets.
H1
Synonym: HRH1
Validated Assay/Platform: Calcium
Description: Histamine is a ubiquitous messenger that mediates a large number of physiological processes. Its actions are mediated by four receptors named H1, H2, H3 and H4 receptors. The H1 histamine receptor is expressed primarily in lung, vasculature and brain where it mediates smooth muscle contraction, food intake and sleep, amongst other actions. Perhaps most notably, antagonists to this receptor are frequently prescribed to treat respiratory allergies.
Platforms Available
Cambridge Bioscience, through our collaboration with ChanTest, offers access to both FLIPRTETRA® and FlexStation® 3 allowing you to select the right balance of speed, throughput and data quality to suit your needs.
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