Gastric Inhibitor Peptide Receptors
Cambridge Bioscience, through our collaboration with ChanTest, offers access to GPCR screening and profiling services to the following gastric inhibitor peptide receptor targets:
Synonym: Glucose-dependent insulinotropic peptide receptor
Validated Assay/Platform: Binding & cAMP
Description: Gastric inhibitory polypeptide (GIP) is a 42 amino acid polypeptide synthesized by K-cells of the duodenum and small intestine. GIP’s principle physiological action is to stimulate insulin secretion from pancreatic β cells in a glucose-dependent manner. Additional effects of GIP have been described, including effects on lipid metabolism, stimulation of glucagons and somatostatin release. GIP exerts its effects by bhinding to its specific receptor, the GIP receptor which belongs to the VIP/guucagon/secretin family of G protein-coupled receptors and is positively coupled to adenylyl cyclase but not to phospholipase C.
Cambridge Bioscience, through our collaboration with ChanTest, offers access to both FLIPRTETRA® and FlexStation® 3 allowing you to select the right balance of speed, throughput and data quality to suit your needs.
To find out more about each of these platforms, please Click Here
Request A No Obligation Quote
To discuss a GPCR screening project, please contact our experienced team by Clicking Here